Proof-of-Concept Program

Turning a promising bio-based idea into something investors and customers will back often requires real-world proof, not just lab results. That’s where the Proof-of-Concept Program from Natural Products Canada comes in. Designed for Canadian startups, SMEs, and research teams working with innovative natural products or technologies, this program helps bridge the gap between development and commercialization by supporting trials and demonstrations that show commercial feasibility. Projects can receive non-repayable funding of up to roughly $350,000, helping offset a meaningful portion of project costs during this critical stage.

The program focuses on later-stage proof-of-concept work rather than basic research, making it especially relevant for businesses in biotechnology, life sciences, clean technology, and other bio-based sectors. Eligible activities may include field trials, pilot-scale demonstrations, or other validation efforts that reduce technical and market risk and make the project more attractive for follow-on investment. Funding is structured to complement private capital, with applicants contributing the remaining project costs, and projects are typically carried out over a defined development window.

Because the Proof-of-Concept Program is available nationally and supports both commercial companies and academic spin-out pathways, it plays a key role in strengthening Canada’s natural products ecosystem. Businesses and researchers considering this opportunity will want to explore how their innovation aligns with the program’s focus and what’s involved in preparing a competitive application.